Tryptomer Tablets – Side Effects, Dosage and Precautions

What is Tryptomer?

Tryptomer Tablet is an effective medicine, used for the treatment of Depression, Neuropathic pain, Bedwetting in children and other conditions. Tryptomer is also used to relieve the symptoms of migraines, tension headaches, and anxiety. It acts as a tricyclic antidepressant, by altering levels of the certain chemical in the brain.


These tablets are manufactured by Wockhardt Limited. Tryptomer Tablets are sold in the packaging of 10 tablets per strip.

    1. Generic Medicine in The Tablet?
    2. Dosage of This Tablet
    3. Working Mechanism of This Medicine
    4. Why is This Tablet Prescribed?
    5. Possible Side Effects of This Medicine
    6. Precautions While Using These Tablets
    7. Using The Medicine During Pregnancy and Breastfeeding
    8. Dosage for Children and Infants
    9. Where to Buy These Tablets?
    10. Reference

Generic Medicine in The Tablet

Each Tryptomer Tablet contains Amitriptyline (A Tertiary Amine – Tricyclic Antidepressant) as the generic medicine.

This medicine may be available in various strengths as of:

  • 10 mg tablets
  • 25 mg tablets
  • 75 mg tablets

Dosage of This Tablet

Take Tryptomer tablets as per your doctor’s guidance. Follow all the labeled instructions while taking the Tryptomer tablet.

Do not chew, crush or break the tablet. Swallow it as a whole. It can be taken with or without food.

The dosage of this medicine varies with the age of the patient and the type of medical condition for which the medicine is being used.

The adult dosage for Tryptomer Tablets is 25 mg three times a day, but dose can be gradually increased up to 150 mg/day.

In the case of adolescent and elderly Patients, lower dosages are recommended. 10 mg twice or three times a day with 20 mg at bedtime is recommended, as they cannot tolerate higher dosage. Dosage should be initiated at a low level and increased gradually.

Working Mechanism of This Medicine

Amitriptyline is a tricyclic antidepressant. It works by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain.

Amitriptyline exerts its action by blocking neuronal re-uptake of noradrenaline and serotonin thus increasing synaptic concentration of serotonin and/or norepinephrine in the central nervous system. Amitriptyline is rapidly absorbed after oral administration.

Distribution: It is widely distributed, crosses the placenta, enters breast milk. Protein binding: Extensive.

Metabolism: Imipramine is metabolized in the liver to the active metabolite Nortriptyline.

Excretion: Drug is excreted mainly in urine. Its effect starts within 2-3 weeks of its administration. The maximum duration of the effect of this medicine is around 6 weeks.

Why is This Tablet Prescribed?

Tryptomer Tablet is used for the treatment of the following diseases and symptoms:

This Tablet may also be prescribed for the problems not listed here. This medication is used as a sedative and is useful in depressed patients with insomnia, restlessness, and nervousness. It helps in improving mood, relieve anxiety and tension, help you sleep better and increases your energy level.

Possible Side Effects of This Medicine

The following is a list of possible side-effects that may occur from the Tryptomer tablet. These side-effects are possible but do not always occur. Consult your doctor if you observe any of the following side-effects.

  • Drowsiness
  • Fatigue
  • Dry mouth
  • Dizziness
  • Lack of sleep
  • Headache
  • Agitation
  • Insomnia
  • Blurred Vision
  • Nausea and Vomiting
  • Constipation or Diarrhoea
  • Hypertension
  • Breast enlargement
  • Heart block
  • Hypotension
  • Fainting
  • Seizures
  • Hallucinations
  • Delusions
  • Confusion
  • Numbness
  • Excitement
  • Anxiety
  • Restlessness
  • Nightmares
  • Weakness
  • Tremor
  • Skin rash
  • Black tongue
  • Unexpected Weight gain or loss
  • Swelling of face, lips, eyelids, tongue, hands, and feet
  • Loss of libido
  • Unusual Bleeding

This is not a complete list of possible side effects of Amitriptyline medication. If you notice any other side-effects not listed above, contact your doctor.

Precautions While Using These Tablets

  • Before using The Tryptomer tablet, inform your doctor about your current list of medications and current health conditions.
  • Some health conditions may make you more susceptible to the side-effects of the drug.
  • This tablet should be taken with caution during medical conditions, such as Hyperthyroidism, Myocardial infarction, Tachycardia, Heart diseases, Old aged patients, Strokes, Angle-closure glaucoma, History of urine retention, Renal Impairment, Hepatic impairment, Chest pain.
  • Take as directed by your doctor or follow the direction printed on the product insert. Ensure that the right amount of medicine should be consumed for prescribed duration only.
  • Take special precautions if you are pregnant or breastfeeding a baby.
  • Before taking Amitriptyline medication, tell your doctor if you have any allergies. This product may contain ingredients, which can cause allergic reactions.
  • This drug may make you dizzy or blur your vision. Alcohol can make you more dizzy or drowsy. Avoid alcoholic beverages.
  • Avoid prolonged exposure to sunlight. It may cause heatstroke, protect from hot weather.
  • Patients should avoid work that requires a high level of mental alertness or judgment while using this medicine, such as driving a vehicle, operating machinery, etc.
  • This medication may increase the risk of suicidal thoughts in children and teenagers; watch them carefully.
  • If you have diabetes, Monitor your blood sugar levels regularly and tell your doctor about the results.
  • This medication should not be discontinued abruptly unless directed by your doctor.

Other Precautions

  • Check the expiry date before taking this or any medication.
  • Always keep the medicines away from the reach of children.
  • Do not take this tablet If the packaging is tampered or torn.
  • Keep the medicine away from sunlight, in a dry and cool place.
  • Do not refrigerate the tablets.

Using The Medicine During Pregnancy and Breastfeeding

This medicine is classified in the Pregnancy Category “C” by FDA. Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women.

It is not safe to take this medicine during pregnancy. This can cause harmful effects on the fetus.

It is also not safe to take this medicine if you are breastfeeding or planning for breastfeeding. Amitriptyline can get mixed with the blood and get transferred to the baby/child, but its effect on an infant is unknown. Limited data suggest that the drug could represent a significant risk to the baby.

Please share your pregnancy status with your doctor if being prescribed by this medicine. Discuss the risks and benefits with your doctor. During pregnancy, this medication should be used only when benefits from the medicine outweigh the possible risks.

Dosage for Children and Infants

While the Higher dosage Amitriptyline is not approved for use in pediatric patients below 12 years. This medicine can be given to children under strict medical supervision.

In case of Nocturnal Enuresis (Bedwetting), children above the age of 6 years can be prescribed 10 to 20 mg dose each day. But, this medicine is strictly not to be given to infants.

This medicine can be very harmful and dangerous for Infants and physically weak children. Please consult your doctor to understand more about the usage of this medicine. Do not self-medicate.

Where to Buy These Tablets?

The tablet is not available as an over the counter or OTC product. It is a ‘prescription-only’ drug. In order to purchase this medicine, a prescription from a qualified Doctor is required. When prescribed, ask the doctor about correct dosage and frequency of the medication.


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