Petogen Injection – Side Effects, Dosage and Why It is Prescribed?

What is Petogen Injection?

Petogen Injection is a female hormonal and long lasting Contraceptive medicine. It helps to regulate ovulation and is used to prevent pregnancy. Petogen injection is classified as an active semisynthetic derivative of progesterone. It is also used to correct menstrual disorders caused due to a lack of this hormone in the body. The injections are made and sold by the Intokem Pharmaceuticals Limited. Injection is sold in the form of 5 ml vials of the medicine, 1 vial in the box.

  1. Generic Medicine in The Injection
  2. Dosage of The Injection
  3. Working Mechanism of Medroxyprogesterone
  4. Why is this Injection Prescribed?
  5. Contraindication of Medroxyprogesterone
  6. What are the Side Effects?
  7. Precautions While using this Injection
  8. Using This Injection during Pregnancy and Breastfeeding
  9. Can this medicine be given to children and infants?
  10. Where to buy this medicine?
  11. Reference

petogen injection

Generic Medicine in The Injection

Each Petogen Injection contains medroxyprogesterone as the generic medicine. It is present in the strength of 150 mg in the injection.

Dosage of The Injection

This is long-term contraceptive given 150 mg once every 3 months(13 weeks). The injection should be given intramuscularly only. The first dose should be given only during the first 5 days of a normal menstrual period, within 5 days postpartum if the patient is not breastfeeding and at the sixth postpartum week if the patient is breastfeeding. Please consult your doctor, as the dosage of injection also depends on patient’s response to the medicine.

Working Mechanism of Medroxyprogesterone

Medroxyprogesterone is a type of female hormone Progestin. This medication is similar to progesterone, given to replace the hormone, in case your body is not making enough of it naturally. This hormone helps women in the regulation of ovulation (the release of an egg from the ovary). Medroxyprogesterone is also used for the treatment of absent/irregular menstrual periods or abnormal uterine bleeding. Medroxyprogesterone is also added to estrogen replacement therapy, which is helpful to reduce the risk of cancer of the uterus.

Why is this Injection Prescribed?

This injection is used for the treatment of following diseases/conditions:

  • A Female contraceptive
  • Control and regulation of menstrual periods
  • Control of ovulation
  • Endometrial hyperplasia
  • Abnormal Uterine Bleeding
  • Amenorrhoea
  • Overgrowth in the lining of the uterus in postmenopausal women undergoing the estrogen hormonal therapy.

Contraindication of Medroxyprogesterone

  • Allergy
  • Possibility of Pregnancy
  • Breast or Uterine cancer
  • Liver Disease
  • Undiagnosed vaginal bleeding
  • Ectopic pregnancy
  • Pruritus in Pregnancy
  • Herpes
  • Idiopathic jaundice
  • Hormone-dependent neoplasms
  • Severe liver-impairment
  • Dubin-Johnson syndrome
  • Rotor Syndrome

What are the Side Effects?

Below are the reported side effects that can occur from use of Petogen injection :

  • Breast pain and tenderness
  • Loss of vision or blurred vision
  • Swelling of face, lips, eyelids, tongue, hands, and feet
  • Shortness of breath
  • Mood swings
  • Unusual tiredness
  • Frequent/burning/painful Urination
  • Unusual Vaginal bleeding
  • Bloating
  • Confusion
  • Fainting
  • Chest/jaw/left arm pain
  • Weakness on one side of body
  • Slurred speech
  • Pain/redness of arms/legs
  • Itching
  • Hair loss
  • Bone loss
  • Blood clots
  • Weight gain/loss
  • Drowsiness
  • Allergy
  • Nocturia
  • Hot flushes
  • Heartburn
  • Chest pain
  • Trouble breathing
  • Acne
  • Dark patches on skin/face
  • Paresthesia
  • Asthma
  • Hematuria
  • Nausea and Vomiting
  • Headaches
  • Nervousness
  • Depression
  • Memory loss
  • Insomnia
  • Increase in ovarian size
  • Mental changes
  • Abdominal discomfort/swelling
  • Gastrointestinal disturbances
  • Limb pain
  • Loss of libido
  • Dizziness
  • Faint feeling
  • Vaginal discharge
  • Vaginal cyst
  • Gynaecomastia
  • Cessation of lactation
  • Dysmenorrhoea
  • Amenorrhoea
  • Breakthrough bleeding
  • Asthenia
  • Bloated feeling
  • Diarrhoea
  • Hair or skin changes

This list is not a comprehensive list of all the possible side effects of this drug.
Consult your doctor immediately if any of these symptoms are experienced on a regular basis.

Precautions While using this Injection

  • The patient’s medical history should be carefully evaluated. It is advised to have regular examination during use.
  • Petogen Injection should be used with caution in patients with Heart disease, kidney disease, high blood pressure, Obesity, high level of cholesterol, epilepsy, asthma, thyroid disorder, severe pelvic pain, migraine headache, seizures, and other conditions.
  • It also decreases calcium level in blood, hence increases the risk of fracture, especially in patients with the history of Osteoporosis. Always have a bone density check and take calcium & vitamin D as you were advised by a doctor.
  • Be sure to have a regular breast exam and gynecology check-ups.
  • Petogen injection should not be used if you have certain medical conditions, such as a history of blood clots, Liver disease, history of bleeding in the brain, cancer of the breast or other female organs.
  • If you get signs of liver problems such as dark urine, feeling tired, not hungry, upset stomach, light-colored stool, vomiting or yellow skin/eyes then call your doctor immediately.
  • Always use sunscreen and wear clothing and eyewear that protects you from the sun.
  • Diabetic patients should be carefully observed while on medication.
  • Petogen Injection should also be used with care in persons with a history of mental depression.
  • Avoid smoking while you are taking the Petogen injection, as it may greatly increase the risk of blood clots.
  • Inform your doctor if you had any recent miscarriage or abortion.
  • Should not use this medicine for a prolonged time.
  • Do not take this medicine if you have peptic ulcers, renal insufficiency, and tuberculosis.
  • Not advised if you have hypertension.
  • It can suppress the antibody response and effect functionality of an immune system.

Other Precautions

  • Take Petogen Injection exactly as prescribed by a qualified doctor.
  • Follow all directions on your prescription label.
  • Do not take the larger amount than prescribed.
  • Should not stop the use immediately without consulting your doctor.
  • Do not store in the bathroom or near a sink.
  • Keep it away from children and pets.
  • Keep the medicine at room temperature and avoid contact with direct sunlight.
  • Do not flush in the toilet or pout them into the drain, unless instructed to do so.

Using Petogen Injection during Pregnancy and Breastfeeding

This medicine is classified by FDA as pregnancy category ‘X’. This medicine is not recommended for use in pregnant women, unless absolutely necessary or the risks clearly outweigh any possible benefit to the patient. Reports have shown positive evidence of fetal abnormalities; however, there is no adequate data. Please do not self-medicate this medicine. Please consult your doctor if the need arises to use this medicine.

Petogen Injection may be considered safe to take if you are breastfeeding or planning to start breastfeeding. Always consult your doctor before using it and discuss all the risks and benefits of this medicine. Based on your health conditions, your doctor may prescribe any other medicine for you.

Can this medicine be given to children and infants?

This medicine is not suitable for children. Petogen injection is not intended to be administered to children and infants.

Where to buy this medicine?

This is an injection, and likewise, it is a prescription-only drug. Though the injections are available in all major drugstores and pharmacies, you will need a Doctor’s prescription to buy it.

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