Lomofen Tablet – Uses, Dosage and Side Effects

What is Lomofen Tablet?

Lomofen tablet is a combination medicine. The medicine is a mixture of antibacterial and anticholinergic drugs. It is used for the treatment of diarrhea, cholera, food poisoning, the inflammatory gut disorder caused due to bacterial infections or protozoa and other conditions. Lomofen tablet is manufactured by RPG Life Sciences Ltd. The tablets are sold in the packaging of 20, or 15, or 10 tablets per strip.

  1. Generic Medicine in The Tablet?
  2. Dosage of This Tablet
  3. Working Mechanism of This Medicine
  4. Why is This Tablet Prescribed?
  5. Possible Side Effects of This Medicine
  6. Precautions While Using These Tablets
  7. Using The Medicine During Pregnancy and Breastfeeding
  8. Dosage for Children and Infants
  9. Where to Buy These Tablets?
  10. Reference

lomofen tablet

Generic Medicine in The Tablet

Each Lomofen Tablet has the following generics medicines, along given is their individual strength:

Furazolidone (Antibacterial Agent) – 50 mg
Diphenoxylate (Antidiarrheal Opioid Agent) – 2.5 mg
Atropine (Anticholinergic Agent) – 0.025 mg

Dosage of This Tablet

The usual dose of this tablet for adults is 10 mg daily – followed by 5 mg every 6 hours until diarrhea under control.

For Children above 12 years: Dosage give should be 5 mg daily in divided doses.

For Children above 6 years: Dosage given should be 2.5 mg daily in divided doses.

Take this tablet orally with water as directed by your Doctor. Do not chew, crush or break the Tablet, Swallow it as a whole. If you feel an upset stomach after taking this tablet, take the next dose with your meals.

Working Mechanism of This Medicine

Lomofen Tablet works by blocking acetylcholine in the body. The individual working of each generic of this medicine can be understood as being described below:

  1. Furazolidone is an antibacterial agent, which especially attacks the protozoa causing the infection in the body. It affects the spread and growth of bacteria by interrupting the enzyme supply required for bacterial growth. It works by altering and damaging the DNA of protozoan microbes.
  2. Diphenoxylate is an anti-diarrhoeal medication. It also has Opioid properties, which helps in reducing the contractions of the intestines. These contraction pushes the food through our gut and comes out in the form of stool. Diphenoxylate reduces the movement and supports the digestive system to retain water from the food. This controls the regular and loose diluted bowel movements in Diarrhea.
  3. Atropine belongs to the class of medication called as anticholinergic drugs. It acts by blocking the activity chemicals (acetylcholine) in the body, thereby producing effects such as reduction of salivary and other body secretions, relief of abdominal pain due to cramps, increase in the heart rate, and widening of the pupil.

Why is This Tablet Prescribed?

Individual uses of all generics of this capsules are being described below:

  • Furazolidone is used in the treatment of burns and diarrhea.
  • Diphenoxylate is used in the treatment of Diarrhea. It should not be used in patients with dysentery (diarrhea with blood).
  • Atropine is used in the treatment of bradycardia and uveitis.

It is also useful in cases of:

  • Diarrhea
  • Cholera
  • Food poisoning
  • Inflammatory gut disorders
  • Enteritis caused by susceptible bacteria or protozoa
  • Giardiasis
  • Bacterial and protozoa enteritis
  • Cycloplegia
  • Mydriasis

Contraindications

Lomofen tablet should not be used if you have the following conditions:

  • Blood traces in Stool or Dysentery
  • Hypersensitivity
  • Hypersensitivity to diphenoxylate or atropine
  • Infants younger than 1 month of age
  • Obstructive jaundice

Possible Side Effects of This Medicine

The generics of Lomofen Tablet with their individual side-effects are listed below:

Furazolidone

  • Allergic reaction
  • Acne
  • Joint pain, Back Pain
  • Decreased blood pressure
  • Dizziness, Headaches
  • Nausea/Vomiting, Stomach upset
  • Weakness
  • Chills, Fever

Diphenoxylate

  • Headaches
  • Nausea
  • Constipation
  • Flatulence

Atropine

  • Dry mouth, Excessive thirst
  • Dry skin
  • Difficulty in urination
  • Dilation of pupil, Photophobia
  • Palpitations
  • Increased heart rate and Arrhythmia
  • Reduced bronchial secretions
  • Flushing (sense of warmth in the face, ears, neck, and trunk)
  • Constipation

Precautions While Using These Tablets

You should take following precautions while administering this medicine:

  • Before using Lomofen tablet, inform your doctor about your current list of medications and current health conditions.
  • Some health conditions may make you more susceptible to the side-effects of the drug.
  • Inform your doctor about any drug or food allergies.
  • Patients suffering from Liver disease, Lung disease, the ulcerative disease should take on medical advice.
  • Lomofen Tablet should be used with caution in patients with kidney and Liver disease. Dose adjustment of the Tablet may be needed. Please consult your doctor.
  • This may cause drowsiness/dizziness as such try to avoid driving and operating any heavy machinery
  • Avoid Alcoholic beverages, as it may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol.
  • Lomofen Tablet may cause excessive drowsiness and calmness with alcohol.
  • Consult your doctor if palpitations or difficulty in swallowing occurs.
  • Consult your doctor immediately if experiencing fall in blood pressure, angioedema, fever, arthralgia or urticaria.

Other Precautions

  • Check the expiry date before taking this or any medication.
  • Always keep the medicines away from the reach of children.
  • Do not take this tablet If the packaging is tampered or torn.
  • Keep the medicine away from sunlight, in a dry and cool place.
  • Do not exceed the recommended dosage
  • Do not crush or chew tablets.
  • Follow the directions written on your medicine label.
  • Keep the tablets in the original pack until it is time to take them.
  • Do not store medicine in the bathroom or near a sink.
  • Always Keep the medicine away from the reach of children and pets.
  • Take this medicine only if you are prescribed by a doctor.

Using The Medicine During Pregnancy and Breastfeeding

This medicine is classified in the Pregnancy Category “C” by FDA. Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women. It is not safe to take this medicine during pregnancy. This can cause harmful effects on the fetus. This should be taken under doctor prescription. Consult a doctor before administering this medicine to a pregnant woman.

Lomofen Tablet is probably unsafe to use during breastfeeding or planning for breastfeeding. Limited human data suggest that the drug could represent a significant risk to the baby. If you are breastfeeding or planning to start breastfeeding, consult a doctor before using this medicine.

Please share your pregnancy status with your doctor if being prescribed by this medicine. Discuss the risks and benefits with your doctor. During pregnancy, this medication should be used only when benefits from the medicine outweigh the possible risks.

Dosage for Children and Infants

These medicinal tablets are not suitable for infants or younger children. However, if necessary, these tablets can be prescribed to children of the age 6 years or over. Always consult a certified Pediatrician before using this medicine for the children. The pediatrician will suggest the correct dosage for the child under his strict observation.

Where to Buy These Tablets?

Lomofen tablet is a ‘prescription-only‘ and it is not available as an over the counter or an OTC product. In order to purchase this medicine, a prescription from a qualified Doctor is required. When prescribed, ask the doctor about correct dosage and frequency of the medication.

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